Kidney pain covid vaccine side effect9/11/2023 ![]() As of October 11, 2021, this emerging highly infectious disease had spread to 237,383,711 individuals throughout the world, with 4,842,716 related deaths reported ( ). The first cluster of COVID-19 cases in individuals associated with the Huanan Seafood Wholesale Market in Wuhan, Hubei Province, China, was reported on Decem( ), then following the worldwide spread of COVID-19, a pandemic was declared by the World Health Organization on Ma( ). Findings in the present case indicate that new-onset IgA vasculitis after receiving mRNA-1273 COVID-19 vaccine can be treated with corticosteroid therapy.Ĭoronavirus disease 2019 (COVID-19) is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain of virus. Over the following 2-week period, serum creatinine level improved from 1.24 to 1.06 mg/dL and proteinuria decreased from 2.98 to 0.36 g/g Cr, though occult blood persisted. Intravenous methylprednisolone at 1000 mg for 3 days was initiated, followed by oral prednisolone (0.6 mg/kg/day). Histopathological features were consistent with IgA vasculitis. ![]() Immunofluorescence also showed diffuse granular mesangial staining (3 +) for IgA. Thus, a kidney biopsy was performed and light microscopy revealed mild mesangial expansion, hypercellularity, and endocapillary hypercellularity, with cellular and fibrocellular crescents observed in three and one, respectively, of a total of 15 glomeruli. Urinalysis indicated severe proteinuria (3 +) and occult blood (3 +). A histopathological examination of skin biopsy specimens was reminiscent of leukocytoclastic vasculitis, though direct immunofluorescence did not indicate IgA deposition within small vessel walls. Although the eruptions spontaneously improved within 5 days, they developed again at 15 days after the second injection. A 47-year-old man with a 10-year medical history of hypertension and hyperuricemia visited our hospital 19 days after receiving an initial mRNA-1273 COVID-19 vaccine injection for purpuric eruption on the legs and dorsal regions of the feet. Here, we present a case of kidney biopsy-proven new-onset IgA vasculitis after receiving the mRNA-1273 (Moderna) COVID-19 vaccination. ![]() She credits her improvement to seeing a physical therapist, who is helping stretch out her muscles.As mRNA COVID-19 vaccines have become widely available, cases of new-onset glomerular disease after receiving COVID-19 vaccination have been reported. Lynch said her back pain still persists after several weeks, but she's a lot more mobile now. Ferrari doesn't have any lingering physical symptoms, either - though she said her depression has gotten worse after having COVID-19. Bartel said she took pain medication for a few days, but is feeling "100% better" now. "I think all of us can agree that, for the most part, our activity level may not have been the same as it was before the pandemic - and obviously Omicron came on later on in the pandemic."Īll three people who reported back pain to Insider said the symptom has either improved or completely resolved since their illness started. "If you're on a tight deadline and you're at your seat typing away for eight hours, you're going to have back pain," Whang said. Viral infections produce inflammation, which can exacerbate underlying health problems and generate new symptoms. Some COVID-19 patients with back pain may be experiencing a flare-up of an existing problem, like arthritis or generalized back pain from sitting too long at the computer. Account icon An icon in the shape of a person's head and shoulders.
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